365 Organic Hemp Protein Powder vs Dymatize ISO100 Whey Isolate
Two of our picks from Best Protein Powders, compared side by side on the specs and trade-offs that actually matter.
Short answer
Between the Dymatize ISO100 Whey Isolate and the 365 Organic Hemp Protein Powder, we recommend the Dymatize ISO100 Whey Isolate ($144.09 when we checked it on 2026-10-12) as the better protein powder for most people. Lean macros and fast post-workout recovery The 365 Organic Hemp Protein Powder ($13.49 when we checked it on 2026-10-12) still makes sense if plant-based eaters who want a clean, simple label.

365 by Whole Foods Market, Organic Hemp Protein Powder Unflavored, 16 oz
$13.49observed
Lowest we have recorded: $9.51 on (18 weekly checks)

Dymatize ISO100 Whey Protein Powder Isolate, Fudge Brownie, 25g of Protein, 5 Pound, 5.5g BCAAs, Less Than 120 Cal., Gluten Free, 1g Fat, 1g Sugar, 2g Carb (70 Servings)
$144.09observed
Lowest we have recorded: $106.99 on (18 weekly checks)
Specs head to head
| Spec | 365 Organic Hemp Protein Powder | Dymatize ISO100 Whey Isolate |
|---|---|---|
| Flavor | Unflavored | Fudge Brownie |
Our take on each
365 Organic Hemp Protein Powder
Best for: Plant-based eaters who want a clean, simple label
This is the no-frills, plant-based option for people who care more about what is not in the tub than about chasing the highest protein number on the label. It is organic hemp seed protein, unflavored, and carries USDA organic, non-GMO, and kosher certifications, so the ingredient list stays short and verifiable.
Hemp is a solid choice if whey does not agree with your stomach, or if you simply prefer to keep things plant-based, and at this price point you are not overthinking a purchase that could otherwise involve a lot of label reading. It comes in a 16 oz size that is easy to keep on a shelf without committing to a huge tub.
The honest tradeoff is flavor and focus. It ships unflavored, so it needs a smoothie or something to mask the taste rather than a plain shake with water, and it leans toward clean sourcing over the sheer protein-per-scoop numbers a dedicated whey isolate delivers. For a plant-based daily staple, it is an easy, affordable choice.
Dymatize ISO100 Whey Isolate
Best for: Lean macros and fast post-workout recovery
ISO100 is the pick when you want protein and not much else cluttering the label. Each serving delivers 25g of protein alongside 5.5g of BCAAs, including 2.7g of L-Leucine, while keeping things tight at 1g fat, 1g sugar, and under 120 calories, numbers that are hard to match once you start comparing tubs side by side.
It is filtered to cut excess lactose and carbs, and the protein itself is broken down into small peptides for faster absorption, exactly why people reach for it right after a workout rather than saving it for later in the day. Dymatize publishes third-party Informed-Choice testing on ISO100, which is the check that matters for anyone who gets drug tested.
The tradeoffs are the ones you would expect from a premium isolate. It carries a premium price per tub, and being whey-based, it is not an option if you are following a plant-based diet. For anyone watching macros closely, it is about as clean as protein powder gets.
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